Biolegend, 387206, PE anti-human CD44 variant 5 (CD44v5) Recombinant Antibody, 100tests

CD44v5, also known as CD44 isoform 5, is a CD44 isoform containing exon10. CD44 is an adhesion molecule involved with multiple functions, including lymphocyte activation, cell-matrix interactions particularly hyaluronic acid, and as a marker of effector memory T-Cells. CD44v5 may be an indicator for tumor presence and progression in certain cancers, such as colon, thymus, breast, and prostate.
100tests
Verified Reactivity: Human
Antibody Type: Recombinant
Host Species: Mouse
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Concentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Excitation Laser: Blue Laser (488 nm)Green Laser (532 nm)/Yellow-Green Laser (561 nm)
RRID: AB_3675114 (BioLegend Cat. No. 387205) AB_3675114 (BioLegend Cat. No. 387206)
Structure: Glycoprotein
Distribution: Epithelial cancers, subset of lymphocytes, subset of monocytes
Cell Type: Epithelial cells, Lymphocytes, Thymocytes
Biology Area: Cancer Biomarkers, Cell Adhesion
Molecular Family: Adhesion Molecules
Antigen References: Barclay AN, et al. 1997. The Leukocyte Antigen FactsBook Academic Press. Haynes BF, et al. 1991. Cancer Cells. 3:347-50. Naor D, et al. 1997. Adv Cancer Res. 71:241-319. Lee S, et al. 2003. Ann of Thorac Surg. 76:213-8.
Gene ID: 960
UniProt: View information about CD44 on UniProt.org
Clone: QA20A79
Regulatory Status: RUO
Other Names: CD44 isoform v5, CD44 exon10
Isotype: Mouse IgG1, κ
Q: What type of PE do you use in your conjugates?
A: We use R-PE in our conjugates.