Biolegend, 399713, PE/Cyanine7 anti-human TGF-β Receptor II Antibody, 25tests

Transforming growth factor beta receptor 2 (TGFbR2 or TGFbRII) forms a heterodimeric complex on the cell surface with TGFbR1. TGFbR2 binds TGF-beta and is important for cell proliferation, wound healing, immunosuppression, and tumorigenesis.
25tests
Verified Reactivity: Human
Antibody Type: Monoclonal
Host Species: Rat
Immunogen: TGFbR2 protein (aa 1-243) expressing transfectants
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation: The antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions.
Concentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Excitation Laser: Blue Laser (488 nm)Green Laser (532 nm)/Yellow-Green Laser (561 nm)
RRID: AB_2927912 (BioLegend Cat. No. 399713) AB_2927912 (BioLegend Cat. No. 399714)
Distribution: B cells, T cells, monocytes, and granulocytes.
Ligand/Receptor: TGFbR2 forms a heterodimeric complex with TGFbR1 and binds TGF-β.
Cell Type: B cells, Monocytes, T cells
Biology Area: Immunology
Molecular Family: Cytokines/Chemokines
Antigen References: Horbelt D, et al. 2010. J Cell Sci. 123:4340-50. Wei CY, et al. 2015. Int J Clin Exp Pathol. 8:14619-29. Numata S, et al. 2008. J Psychiatr Res. 42:425-32.
Gene ID: 7048
UniProt: View information about TGF-beta Receptor II on UniProt.org
Clone: W17055E
Regulatory Status: RUO
Other Names: TGFRII, TGFR2, TGFR-2, TβRII, TGFbeta-RII, TGF-Beta Receptor Type II, TGF-Beta Receptor Type-2
Isotype: Rat IgG2b, κ