Biolegend, 437014, ELISA MAX™ Deluxe Set Human Pro IL-1β, 5plates

IL-1 refers to two proteins (IL-1α and IL-1β), which are the products of distinct genes that are recognized by the same cell surface receptors. Human IL-1β is a potent immuno-modulator that mediates a wide range of immune and inflammatory responses, including the activation of B and T cells. Pro-IL-1β is converted to its mature form through proteolytic cleavage by caspase-1 (also known as IL-1β-converting enzyme or ICE). This intracellular processing produces the mature active peptide that can be secreted and represents a key step in the inflammatory response. IL-1β  is expressed in several cell types, including monocytes, tissue macrophages, Langerhan cells, dendritic cells, T lymphocytes, B lymphocytes and natural killer cells. IL-1β plays a pathogenic role in Type 1 and Type 2 diabetes, rheumatoid arthritis, and osteoarthritis among other diseases. BioLegend’s ELISA MAX™ Deluxe Set Pro IL-1β contains the components necessary for the accurate quantification of natural and recombinant pro-IL-1β. The set is designed for cost-effective and accurate quantification of human pro-IL-1β in cell lysate samples. BioLegend’s ELISA MAX™ Deluxe Sets are sensitive, accurate, and robust.
5plates
Verified Reactivity: Human
Application: ELISA
Sensitivity: 0.08 ng/mL
Standard Range: 0.313 - 20 ng/mL
Cell Type: Astrocytes, B cells, Dendritic cells, Fibroblasts, Langerhans cells, Macrophages, Microglia, Monocytes, NK cells, T cells
Biology Area: Cell Biology, Immunology, Innate Immunity, Neuroinflammation, Neuroscience
Molecular Family: Cytokine/Chemokine Receptors
Gene ID: NA
UniProt: View information about Pro IL-1beta on UniProt.org
Regulatory Status: RUO
Other Names: Preinterleukin 1 beta, Pro-IL-1 beta, Pro IL1b, Pro IL-1F2, pro-interleukin-1-beta
Q: Do the ELISA MAX™ Deluxe Sets come with plates?
A: No, ELISA MAX™ Deluxe Sets do not come with plates. Coating Buffer and Assay Diluent (for blocking and dilutions) are included in these sets. Plates can be ordered separately (Cat No. 423501), and instructions for coating the plates are in the sets’ product manuals.