Biolegend, 663705, Purified anti-, 25μg

Sigma transcription factor controlling the regulation of genes is required for protection against external stresses. Possibly, it affects the expression of katE (catalase HPII), xthA (endonuclease III), the appABC operon, and other genes by modifying the affinity of RNA polymerase for the promoters.
25μg
Verified Reactivity: E. coli
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: Recombinant protein
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/mL
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: WB - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by western blotting. For western blotting, the suggested use of this reagent is 0.0625 - 1.0 µg/mL. It is recommended that the reagent be titrated for optimal performance for each application.
Application Notes: Previously item# W0009 from Neoclone. Clone 1RS1 does not react with Shigella, Vibrio, Pseudomonas, Rhodobacter, Agrobacterium, Streptococcus, Arthobacter, or Borrelia. It recognizes epitope 33-256. Additional reported applications (for the relevant formats) include: functional assay.
Application References(PubMed link indicates BioLegend citation): Nguyen LH, et al. 1993. Biochemistry 32:11112.
RRID: AB_2832841 (BioLegend Cat. No. 663705) AB_2832842 (BioLegend Cat. No. 663706)
Structure: Sigma S (σS) is a 38 kD transcription factor of E. coli RNA polymerase.
Biology Area: Cell Biology, Transcription Factors
Molecular Family: Nuclear Markers
Gene ID: 947210
UniProt: View information about RNA Sigma S on UniProt.org
Clone: 1RS1
Regulatory Status: RUO
Other Names: Sigma 38, rpoS, appR, katF, nur, otsX, sigS, RNA Polymerase
Isotype: Mouse IgG1