Biolegend, 666203, Alexa Fluor® 594 anti-eIF4A1 Antibody, 25μg

EIF4A1 is an ATP-dependent RNA helicase. It can form the eIF4F complex, which is involved in translation initiation by binding with the 5' m 7 GTP cap of the mRNA. It could unwind mRNA secondary structure at the 5’ UTR region and lead to the small ribosomal subunit binding and followed scanning of the initiator codon.
25μg
Verified Reactivity: Human, Mouse, Rat, Hamster
Antibody Type: Monoclonal
Host Species: Rat
Immunogen: Human EIF4A1 Peptide (3-19 a.a.) conjugated to KLH
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 594 under optimal conditions.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application: ICC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunocytochemistry. For immunocytochemistry, a concentration range of 0.1 - 0.4 μg/ml is recommended. It is recommended that the reagent be titrated for optimal performance for each application. * Alexa Fluor® 594 has an excitation maximum of 590 nm, and a maximum emission of 617 nm. Alexa Fluor® and Pacific Blue™ are trademarks of Life Technologies Corporation.View full statement regarding label licenses
RRID: AB_2810694 (BioLegend Cat. No. 666203) AB_2810695 (BioLegend Cat. No. 666204)
Distribution: Cytoplasm
Function: Translation initiation
Interaction: eIF4 complex
Biology Area: Cell Biology, Cell Proliferation and Viability, Neurodegeneration, Neuroscience, Protein Misfolding and Aggregation, Protein Synthesis, Signal Transduction
Gene ID: 1973
UniProt: View information about EIF4A1 on UniProt.org
Clone: W17130C
Regulatory Status: RUO
Other Names: EIF4A1, Eukaryotic Translation Initiation Factor 4A1
Isotype: Rat IgG2a, κ