Biolegend, 847002, Purified anti-CD66e Antibody, 100μg

Carcinoembryonic antigen (CEA), also known as CD66e, is a glycoprotein involved in cell adhesion and intracellular signaling. It is normally produced during fetal development in the gut, and its production stops before birth. CEA is re-expressed in increased amounts in Intestinal Carcinomas and several other tumors.
100μg
Verified Reactivity: Human
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: Recombinant human CEA.
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: IHC-P - Quality testedIHC-F, WB - Reported in the literature, not verified in house
Recommended Usage: Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 0.5 - 1.0 µg/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
RRID: AB_2629664 (BioLegend Cat. No. 847002)
Structure: CEA is a 702 amino acid protein with a molecular mass of 77 kD.
Distribution: Tissue distribution: intestine, colon, and blood. Cellular distribution: extracellular and plasma membrane.
Function: CEA is a biomarker for gastrointestinal cancers and may promote tumor development through its role as an adhesion molecule.
Biology Area: Cell Adhesion, Cell Biology
Antigen References: 1. Go VL. 1976. Cancer. 37:562. PubMed 2. DeLellis RA, et al. 1978. Am. J. Clin. Pathol. 70:587. PubMed 3. Kamino H, et al. 1988. Cancer. 61:1142. PubMed 4. Tron V, et al. 1987. Arch. Pathol. Lab. Med. 111:291. PubMed
Gene ID: 1048
UniProt: View information about CD66e on UniProt.org
Clone: BSB-13
Regulatory Status: RUO
Other Names: Carcinoembryonic antigen, CEA, CEACAM5, CD66 antigen, CD66e
Isotype: Mouse IgG1, κ