Biolegend, 915206, Purified anti-BRST-3 Antibody, 100μg

BRST-3, also known as TAG-72 (Tumor Associated Glycoprotein-72), a high molecular weight (220-400 kD) glycoprotein complex, is expressed by a wide variety of human adenocarcinomas.
100μg
Verified Reactivity: Human
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: This antibody was generated against a membrane-enriched fraction of a breast carcinoma metastatic to the liver.
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: IHC-P - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 2.0 - 10 µg/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
Application Notes: B72.3 is reactive with a broad spectrum of epithelial malignancies in human, including invasive ductal carcinoma, lung carcinomas, ovarian, gastric and colonic adenocarcinomas. It appears to be non-reactive or weakly reactive to most normal tissues.
Application References(PubMed link indicates BioLegend citation): Liu G, et al. 2008. Eur. J. Nucl. Med. Mol. Imaging 35(2):272. Lyda MH, et al. 2000. Hum. Pathol. 31(8):980. Clemo FA, et al. 1995. Vet. Pathol. 32:147. (IHC) Colcher D, et al. 1981. Proc. Natl. Acad. Sci. USA 78:3199.
RRID: AB_2616965 (BioLegend Cat. No. 915206)
Biology Area: Cancer Biomarkers, Cell Biology
Gene ID: NA
UniProt: View information about BRST-3 on UniProt.org
Clone: B72.3
Regulatory Status: RUO
Other Names: BRST3
Isotype: Mouse IgG1, κ