CST, 35136S, STEEP Antibody

Polyclonal Antibody for studying STEEP. Validated for Western Blotting,Immunoprecipitation. Highly specific and rigorously validated in-house, STEEP Antibody (CST #35136) is ready to ship. Product Usage Information Western Blotting: 1:1000 Immunoprecipitation: 1:50 Storage Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at -20°C. Do not aliquot the antibody . Protocol Available protocols: Western Blotting, Immunoprecipitation Specificity / Sensitivity STEEP Antibody recognizes endogenous levels of total STEEP protein. Species Reactivity: Human, Mouse, Rat Source / Purification Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human STEEP protein. Antibodies are purified by peptide affinity chromatography. Background STING ER exit protein (STEEP) is a highly conserved, ubiquitously expressed protein, which has been shown to be a positive regulator of the cGAS-STING signaling pathway. Mechanistically, research studies have demonstrated that STEEP constitutively interacts with STING to coordinate STING ER-to-Golgi trafficking, which is an essential step to ensure productive STING-dependent signaling and gene expression in response to viral infection (1). Alternate Names CXorf56; FLJ22965; MRX107; STEEP1; STING ER exit protein; STING1 ER exit protein 1; UPF0428 protein CXorf56 Specification REACTIVITY: H M R SENSITIVITY: Endogenous MW (kDa): 28 SOURCE: Rabbit