Product Description
Size: 20ul / 150ul
The BNIP2 (10361-1-AP) by Proteintech is a Polyclonal antibody targeting BNIP2 in WB, IF/ICC, ELISA applications with reactivity to human, mouse samples
10361-1-AP targets BNIP2 in WB, IF/ICC, ELISA applications and shows reactivity with human, mouse samples.
Tested Applications
Positive WB detected in: HCT 116 cells, MCF-7 cells, MDA-MB-231 cells, SW480 cells
Positive IF/ICC detected in: HeLa cells, RAW 264.7 cells
Recommended dilution
Western Blot (WB): WB : 1:500-1:1000
Immunofluorescence (IF)/ICC: IF/ICC : 1:50-1:500
Background Information
BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 (BNIP2) is also named as PRKACN2. BNIP2 is developmentally regulated may suggest a role of this gene in those brain areas where the differentiation is orchestrated by estradiol. The expression of BNIP2 was inhibited by estradiol. BNIP2 is implicated in the suppression of cell death and interacts with the BCL-2 and adenovirus E1B 19 kDa proteins. BNIP2 is highly expressed in patients with favorable neuroblastoma (NB) (PMID: 25611382).
Specification
Tested Reactivity: human, mouse
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Immunogen: CatNo: Ag0403 Product name: Recombinant human BNIP2 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 144-313 aa of BC002461 Sequence: MKAIEPYKKVISHGGYYGDGLNAIVVFAVCFMPESSQPNYRYLMDNLFKYVIGTLELLVAENYMIVYLNGATTRRKMPSLGWLRKCYQQIDRRLRKNLKSLIIVHPSWFIRTLLAVTRPFISSKFSQKIRYVFNLAELAELVPMEYVGIPECIKQVDQELNGKQDEPKNE Predict reactive species
Full Name: BCL2/adenovirus E1B 19kDa interacting protein 2
Calculated Molecular Weight: 36 kDa
Observed Molecular Weight: 43 kDa
GenBank Accession Number: BC002461
Gene Symbol: BNIP2
Gene ID (NCBI): 663
RRID: AB_3085366
Conjugate: Unconjugated
Form: Liquid
Purification Method: Antigen affinity purification
UNIPROT ID: Q12982
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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