Product Description
Size: 20ul / 150ul
The PGF/PIGF (10642-1-AP) by Proteintech is a Polyclonal antibody targeting PGF/PIGF in IHC, ELISA applications with reactivity to human, mouse samples
10642-1-AP targets PGF/PIGF in IHC, IF, ELISA applications and shows reactivity with human, mouse samples.
Tested Applications
Positive IHC detected in: human placenta tissue, human breast cancer tissue, human kidney tissue, human meningioma tissue, mouse kidney tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0
Recommended dilution
Immunohistochemistry (IHC): IHC : 1:200-1:800
Background Information
Placenta growth factor (PLGF) is also named as PGF and PGFL. PGF is a homodimeric glycoprotein, 46-50 kDa in size, belonging to the vascular endothelial growth factor (VEGF) sub-family. It plays an important role in pathological VEGF-driven angiogenesis. PLGF is expressed not only in placental cells but also in colon and mammary carcinomas. It acts as a primary inflammatory instigator of atherosclerotic plaque instability and thus may be useful as a risk-predicting biomarker in patients with acute coronary syndromes (ACS).
Specification
Tested Reactivity: human, mouse
Cited Reactivity: human, mouse, rat
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Immunogen: CatNo: Ag0969 Product name: Recombinant human PGF protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-170 aa of BC007789 Sequence: MPVMRLFPCFLQLLAGLALPAVPPQQWALSAGNGSSEVEVVPFQEVWGRSYCRALERLVDVVSEYPSEVEHMFSPSCVSLLRCTGCCGDENLHCVPVETANVTMQLLKIRSGDRPSYVELTFSQHVRCECRPLREKMKPERRRPKGRGKRRREKQRPTDCHLCGDAVPRR Predict reactive species
Full Name: placental growth factor
Calculated Molecular Weight: 25 kDa
Observed Molecular Weight: 50 kDa
GenBank Accession Number: BC007789
Gene Symbol: PGF
Gene ID (NCBI): 5228
RRID: AB_2161061
Conjugate: Unconjugated
Form: Liquid
Purification Method: Antigen affinity purification
UNIPROT ID: P49763
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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