Proteintech, 10691-1-AP, E2F6 Polyclonal antibody

Size: 20ul / 150ul The E2F6 (10691-1-AP) by Proteintech is a Polyclonal antibody targeting E2F6 in WB, ELISA applications with reactivity to human samples 10691-1-AP targets E2F6 in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: A549 cells, HepG2 cells, HuH-7 cells, K-562 cells Recommended dilution Western Blot (WB): WB : 1:500-1:2000 Background Information E2F6 is a member of the E2F family of transcription factors, which play important roles in cell cycle regulation and gene expression. E2F6 is highly expressed in many types of cancer and is associated with poor prognosis. It is involved in the regulation of cell proliferation and can promote tumor growth. E2F6 knockdown significantly reduces the proliferative ability of glioma cells (PMID: 38071912). Additionally, E2F6 is related to immune activation markers, tumor immune cell infiltration, and immune regulators, making it a potential biomarker for predicting the response to cancer immunotherapy. Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag1029 Product name: Recombinant human E2F6 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-281 aa of BC008348 Sequence: MSQQRPARKLPSLLLDPTEETVRRRCRDPINVEGLLPSKIRINLEDNVQYVSMRKALKVKRPRFDVSLVYLTRKFMDLVRSAPGGILDLNKVATKLGVRKRRVYDITNVLDGIDLVEKKSKNHIRWIGSDLSNFGAVPQQKKLQEELSDLSAMEDALDELIKDCAQQLFELTDDKENERLAYVTYQDIHSIQAFHEQIVIAVKAPAETRLDVPAPREDSITVHIRSTNGPIDVYLCEVEQGQTSNKRSEGVGTSSSESTHPEGPEEEENPQQSEELLEVSN Predict reactive species Full Name: E2F transcription factor 6 Calculated Molecular Weight: 32 kDa Observed Molecular Weight: 37 kDa GenBank Accession Number: BC008348 Gene Symbol: E2F6 Gene ID (NCBI): 1876 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: O75461 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.