Product Description
Size: 20ul / 150ul
The PLAGL2 (11540-1-AP) by Proteintech is a Polyclonal antibody targeting PLAGL2 in WB, ELISA applications with reactivity to human, mouse samples
11540-1-AP targets PLAGL2 in WB, IHC, IF, IP, ChIP, ELISA applications and shows reactivity with human, mouse samples.
Tested Applications
Positive WB detected in: Raji cells, mouse kidney tissue
Recommended dilution
Western Blot (WB): WB : 1:1000-1:4000
Background Information
PLAGL2, also named KIAA0198, belongs to the krueppel C2H2-type zinc-finger protein family. It shows weak transcriptional activatory activity. PLAGL2, a proto-oncogene, is implicated in a variety of cancers including acute myeloid leukemia (AML), malignant glioma, colon cancer, and lung adenocarcinoma. PLAGL2 can function as a tumor suppressor by initiating cell cycle arrest and apoptosis. The calculated molecular weight of PLAGL2 is 55 kDa, but the SUMO1-modifIed form is 68 kDa (PMID: 30535429).
Specification
Tested Reactivity: human, mouse
Cited Reactivity: human, mouse
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Immunogen: CatNo: Ag2137 Product name: Recombinant human PLAGL2 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 194-496 aa of BC023655 Sequence: DHCDRRFYTRKDVRRHLVVHTGRKDFLCQYCAQRFGRKDHLTRHVKKSHSQELLKIKTEPVDMLGLLSCSSTVSVKEELSPVLCMASRDVMGTKAFPGMLPMGMYGAHIPTMPSTGVPHSLVHNTLPMGMSYPLESSPISSPAQLPPKYQLGSTSYLPDKLPKVEVDSFLAELPGSLSLSSAEPQPASPQPAAAAALLDEALLAKSPANLSEALCAANVDFSHLLGFLPLNLPPCNPPGATGGLVMGYSQAEAQPLLTTLQAQPQDSPGAGGPLNFGPLHSLPPVFTSGLSSTTLPRFHQAFQ Predict reactive species
Full Name: pleiomorphic adenoma gene-like 2
Calculated Molecular Weight: 496 aa, 55 kDa
Observed Molecular Weight: 50-55 kDa, 70 kDa
GenBank Accession Number: BC023655
Gene Symbol: PLAGL2
Gene ID (NCBI): 5326
RRID: AB_2165035
Conjugate: Unconjugated
Form: Liquid
Purification Method: Antigen affinity purification
UNIPROT ID: Q9UPG8
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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