Product Description
Size: 20ul / 150ul
The NEK11 (12710-1-AP) by Proteintech is a Polyclonal antibody targeting NEK11 in WB, ELISA applications with reactivity to human, mouse, rat samples
12710-1-AP targets NEK11 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Applications
Positive WB detected in: HEK-293T cells, HL-60 cells, HeLa cells, L02 cells
Recommended dilution
Western Blot (WB): WB : 1:500-1:1000
Background Information
NEK11(Serine/threonine-protein kinase) belongs to the NIMA family of kinases, which are involved in DNA replication and genotoxic stress responses.It controls degradation of CDC25A by directly phosphorylating it on residues whose phosphorylation is required for BTRC-mediated polyubiquitination and degradation.It has 4 isoforms produced by alternative splicing.
Specification
Tested Reactivity: human, mouse, rat
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Immunogen: CatNo: Ag3392 Product name: Recombinant human NEK11 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-300 aa of BC028587 Sequence: MLKFQEAAKCVSGSTAISTYPKTLIARRYVLQQKLGSGSFGTVYLVSDKKAKRGEELKVLKEISVGELNPNETVQANLEAQLLSKLDHPAIVKFHASFVEQDNFCIITEYCEGRDLDDKIQEYKQAGKIFPENQIIEWFIQLLLGVDYMHERRILHRDLKSKNVFLKNNLLKIGDFGVSRLLMGSCDLATTLTGTPHYMSPEALKHQGYDTKSDIWSLACILYEMCCMNHAFAGSNFLSIVLKIVEGDTPSLPERYPKELNAIMESMLNKNPSLRPSAIEILKIPYLDEQLQNLMCRYSE Predict reactive species
Full Name: NIMA (never in mitosis gene a)- related kinase 11
Calculated Molecular Weight: 54 kDa, 74 kDa
Observed Molecular Weight: 70-75 kDa
GenBank Accession Number: BC028587
Gene Symbol: NEK11
Gene ID (NCBI): 79858
RRID: AB_2150345
Conjugate: Unconjugated
Form: Liquid
Purification Method: Antigen affinity purification
UNIPROT ID: Q8NG66
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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