Product Description
Size: 20ul / 100ul
The Phospho-RCC1 (Ser11) (14444-1-AP) by Proteintech is a Polyclonal antibody targeting Phospho-RCC1 (Ser11) in WB, ELISA applications with reactivity to human samples
14444-1-AP targets Phospho-RCC1 (Ser11) in WB, ELISA applications and shows reactivity with human samples.
Tested Applications
Positive WB detected in: A431 cells
Recommended dilution
Western Blot (WB): WB : 1:1000-1:8000
Background Information
CHC1, also named as RCC1, promotes the exchange of ran-bound gdp by gtp. It is involved in the regulation of onset of chromosome condensation in the S-phase. Phosphorylation of RCC1 on serines located in or near its nuclear localization signal activates RCC1 to generate RanGTP on mitotic chromosomes, which is required for spindle assembly and chromosome segregation. This antibody is a rabbit polyclonal antibody raised against human phospho-CHC1(Ser11) antigen.
Specification
Tested Reactivity: human
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Immunogen: Peptide Predict reactive species
Full Name: regulator of chromosome condensation 1
Calculated Molecular Weight: 48 kDa
Observed Molecular Weight: 45-50 kDa
GenBank Accession Number: NM_001048194
Gene Symbol: RCC1
Gene ID (NCBI): 1104
RRID: AB_2179583
Conjugate: Unconjugated
Form: Liquid
Purification Method: Antigen affinity purification
UNIPROT ID: P18754
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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