Proteintech, 15935-1-AP, ABCD4 Polyclonal antibody

Size: 20ul / 150ul The ABCD4 (15935-1-AP) by Proteintech is a Polyclonal antibody targeting ABCD4 in WB, ELISA applications with reactivity to human, mouse samples 15935-1-AP targets ABCD4 in WB, ELISA applications and shows reactivity with human, mouse samples. Tested Applications Positive WB detected in: HeLa cells, HepG2 cells, Jurkat cells, mouse liver tissue, mouse skeletal muscle tissue Recommended dilution Western Blot (WB): WB : 1:500-1:2000 Background Information ABCD4, also known as P70R, PMP69, and PXMP1L, belongs to the ATP-binding cassette (ABC) transporter superfamily. ABCD4 Lysosomal membrane protein that transports cobalamin (Vitamin B12) from the lysosomal lumen to the cytosol in an ATP-dependent manner (PMID: 22922874, 33845046, 28572511). ABCD4 is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. Mutations in ABCD4 cause a new inborn error of vitamin B12 metabolism, which is related to methylmalonic aciduria and homocystinuria type cblJ (MAHCJ). Specification Tested Reactivity: human, mouse Cited Reactivity: mouse Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag8783 Product name: Recombinant human ABCD4 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 335-606 aa of BC012815 Sequence: SDVAGYTHRIGQLRETLLDMSLKSQDCEILGESKWGLDTPPGWPAAEPADTAFLLERVSISAPSSDKPLIKDLSLKISEGQSLLITGNTGTGKTSLLRVLGGLWTSTRGSVQMLTDFGPHGVLFLPQKPFFTDGTLREQVIYPLKEVYPDSGSADDERILRFLELAGLSNLVARTEGLDQQVDWNWYDVLSPGEMQRLSFARLFYLQPKYAVLDEATSALTEEVESELYRIGQQLGMTFISVGHRQSLEKFHSLVLKLCGGGRWELMRIKVE Predict reactive species Full Name: ATP-binding cassette, sub-family D (ALD), member 4 Calculated Molecular Weight: 606 aa, 69 kDa Observed Molecular Weight: 70 kDa GenBank Accession Number: BC012815 Gene Symbol: ABCD4 Gene ID (NCBI): 5826 RRID: AB_3085475 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: O14678 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.