Proteintech, 16130-1-AP, INTS4 Polyclonal antibody

Size: 20ul / 150ul The INTS4 (16130-1-AP) by Proteintech is a Polyclonal antibody targeting INTS4 in WB, ELISA applications with reactivity to human, mouse, rat samples 16130-1-AP targets INTS4 in WB, ELISA applications and shows reactivity with human, mouse, rat samples. Tested Applications Positive WB detected in: HeLa cells, HepG2 cells, Jurkat cells, MCF-7 cells Recommended dilution Western Blot (WB): WB : 1:500-1:2000 Background Information Integrator complex subunit 4 (INTS4), a helical repeat protein, plays a key role in stabilizing nuclease domains and other components. INTS4 is a specific and conserved interaction partner of INTS9/11 heterodimer that does not interact with either subunit individually (PMID: 29471365). INTS4 plays a role in achieving a compact nuclease/pseudonuclease configuration resembling that observed for CPSF73/100 in the histone-processing machinery (PMID: 33548203). Specification Tested Reactivity: human, mouse, rat Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag9116 Product name: Recombinant human INTS4 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-331 aa of BC009995 Sequence: MAAHLKKRVYEEFTKVVQPQEEIATKKLRLTKPSKSAALHIDLCKATSPADALQYLLQFARKPVEAESVEGVVRILLEHYYKENDPSVRLKIASLLGLLSKTAGFSPDCIMDDAINILQNEKSHQVLAQLLDTLLAIGTKLPENQAIQMRLVDVACKHLTDTSHGVRNKCLQLLGNLGSLEKSVTKDAEGLAARDVQKIIGDYFSDQDPRVRTAAIKAMLQLHERGLKLHQTIYNQACKLLSDDYEQVRSAAVQLIWVVSQLYPESIVPIPSSNEEIRLVDDAFGKICHMVSDGSWVVRVQAAKLLGSMEQVSSHFLEQTLDKKLMSDLRR Predict reactive species Full Name: integrator complex subunit 4 Calculated Molecular Weight: 963aa,108 kDa; 505aa,57 kDa Observed Molecular Weight: 108 kDa GenBank Accession Number: BC009995 Gene Symbol: INTS4 Gene ID (NCBI): 92105 RRID: AB_2296175 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: Q96HW7 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.