Proteintech, 16587-1-AP, NUPL2 Polyclonal antibody

Size: 20ul / 150ul The NUPL2 (16587-1-AP) by Proteintech is a Polyclonal antibody targeting NUPL2 in WB, ELISA applications with reactivity to human, mouse, rat samples 16587-1-AP targets NUPL2 in WB, ELISA applications and shows reactivity with human, mouse, rat samples. Tested Applications Positive WB detected in: HEK-293 cells, human liver tissue, L02 cells Recommended dilution Western Blot (WB): WB : 1:500-1:1000 Background Information NUPL2 (also known as NLP-1, or hCG1) is an ubiquitous nuclear protein containing many phenylalanine-glycine (FG) repeats. As the functional orthologue of the budding yeast Nup42/Rip1 nucleoporin, NUPL2 is required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm (PMID: 10610322). In case of infection by HIV-1, it may participate in the docking of viral Vpr at the nuclear envelope (PMID: 16000379). NUPL2 localizes to the nuclear envelope and could also be mobile within the nucleus. It promotes CRM1-dependent nuclear protein export (PMID: 22250199). Specification Tested Reactivity: human, mouse, rat Cited Reactivity: human Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag8816 Product name: Recombinant human NUPL2 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 1-224 aa of BC005327 Sequence: MAICQFFLQGRCRFGDRCWNEHPGARGAGGGRQQPQQQPSGNNRRGWNTTSQRYSNVIQPSSFSKSTPWGGSRDQEKPYFSSFDSGASTNRKEGFGLSENPFASLSPDEQKDEKKLLEGIVKDMEVWESSGQWMFSVYSPVKKKPNISGFTDISPEELRLEYHNFLTSNNLQSYLNSVQRLINQWRNRVNELKSLNISTKVALKCLWKIYTHLSPKIYGPDCAL Predict reactive species Full Name: nucleoporin like 2 Calculated Molecular Weight: 45 kDa Observed Molecular Weight: 45 kDa, 33-36 kDa GenBank Accession Number: BC005327 Gene Symbol: NUPL2 Gene ID (NCBI): 11097 RRID: AB_2267702 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: O15504 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.