Product Description
Size: 20ul / 150ul
The OBFC2A (16719-1-AP) by Proteintech is a Polyclonal antibody targeting OBFC2A in WB, ELISA applications with reactivity to human, mouse, rat samples
16719-1-AP targets OBFC2A in WB, IP, ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Applications
Positive WB detected in: COLO 320 cells
Recommended dilution
Western Blot (WB): WB : 1:500-1:1000
Background Information
Single-stranded DNA (ssDNA)-binding proteins (SSBs) are ubiquitous and essential for a variety of DNA metabolic processes, including recombination, replication, and detection and repair of damage. SSBs have multiple roles in binding and sequestering ssDNA, detecting DNA damage, stimulating nucleases, helicases and strand-exchange proteins, activating transcription and mediating protein-protein interactions [PMID:18449195] Human single-stranded DNA-binding protein 1 (hSSB1), encoded by OBFC2B, is characterized as an essential factor for the initiation of DNA damage checkpoints and the maintenance of genomic stability [PMID:22940690].
Specification
Tested Reactivity: human, mouse, rat
Cited Reactivity: human, mouse
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Immunogen: CatNo: Ag10158 Product name: Recombinant human OBFC2A protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-124 aa of BC107723 Sequence: MWKGCLTLYTGRGGELQKIGEFCMVYSEVPNFSEPNPDYRGQQNKGAQSEQKNNSMNSNMGTGTFGPVGNGVHTGPESREHQFSHAGRSNGRGLINPQLQGTASNQTVMTTISNGRDPRRAFKR Predict reactive species
Full Name: oligonucleotide/oligosaccharide-binding fold containing 2A
Calculated Molecular Weight: 124 aa, 14 kDa
Observed Molecular Weight: 22 kDa
GenBank Accession Number: BC107723
Gene Symbol: OBFC2A
Gene ID (NCBI): 64859
RRID: AB_2156021
Conjugate: Unconjugated
Form: Liquid
Purification Method: Antigen affinity purification
UNIPROT ID: Q96AH0
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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