Product Description
Size: 20ul / 150ul
The ADPRM (17017-1-AP) by Proteintech is a Polyclonal antibody targeting ADPRM in WB, ELISA applications with reactivity to human, mouse, rat, pig samples
17017-1-AP targets ADPRM in WB, ELISA applications and shows reactivity with human, mouse, rat, pig samples.
Tested Applications
Positive WB detected in: mouse brain tissue, rat brain tissue, pig brain tissue
Recommended dilution
Western Blot (WB): WB : 1:1000-1:4000
Background Information
ADPRM (ADP-ribose/CDP-alcohol diphosphatase, manganese dependent) is a manganese-dependent glycophosphatase primarily responsible for the breakdown of molecules such as ADP-ribose, IDP-ribose, CDP-glycerol, CDP-choline and CDP-ethanolamine in the cell. The protein is predicted to be located in the cytoplasm and possesses 2',3'-cyclic nucleotide 2'-phosphodiesterase activity, manganese ion-binding activity, and pyrophosphatase activity. ADPRM plays an important role in embryonic development, particularly in the formation of the heart and lungs. In addition, ADPRM may be involved in immune cell signaling, acting as a second messenger for ADP-ribose to activate TRPM2, which in turn regulates oxidative/nitrosative stress.
Specification
Tested Reactivity: human, mouse, rat, pig
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Immunogen: CatNo: Ag9997 Product name: Recombinant human C17orf48 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-205 aa of BC001294 Sequence: MDDKPNPEALSDSSERLFSFGVIADVQFADLEDGFNFQGTRRRYYRHSLLHLQGAIEDWNNESSMPCCVLQLGDIIDGYNAQYNASKKSLELVMDMFKRLKVPVHHTWGNHEFYNFSREYLTHSKLNTKFLEDQIVHHPETMPSEDYYAYHFVPFPKFRFILLDAYDLSVLGVDQSSPKYEQCMKILREHNPNTELNSPQGELFL Predict reactive species
Full Name: chromosome 17 open reading frame 48
Calculated Molecular Weight: 40 kDa
Observed Molecular Weight: 45 kDa
GenBank Accession Number: BC001294
Gene Symbol: C17orf48
Gene ID (NCBI): 56985
Conjugate: Unconjugated
Form: Liquid
Purification Method: Antigen affinity purification
UNIPROT ID: Q3LIE5
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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