Proteintech, 17187-1-AP, ZFP64 Polyclonal antibody

Size: 20ul / 150ul The ZFP64 (17187-1-AP) by Proteintech is a Polyclonal antibody targeting ZFP64 in WB, ELISA applications with reactivity to human, mouse, rat samples 17187-1-AP targets ZFP64 in WB, IF, ChIP, ELISA applications and shows reactivity with human, mouse, rat samples. Tested Applications Positive WB detected in: mouse spleen tissue, HEK-293 cells Recommended dilution Western Blot (WB): WB : 1:500-1:1000 Background Information ZFP64 (also known as ZNF338) is a member of the Krüppel C2H2-type zinc finger family. ZFP64 is a coactivator of Notch1, mediating mesenchymal cell differentiation. ZFP64 expression was up-regulated in mouse peritoneal macrophages in response to stimulation with the TLR4 ligand LPS with a 2-fold increase. The MLL gene encoding the MLL fusion protein is easily activated by ZFP64. ZFP64 is essential for the continuous production of MLL fusion proteins in blood cancer and produces more cancer cells. Since ZFP64 deletion completely and specifically inhibits MLL fusion protein production and leukemia cascade growth, it is an ideal drug target. Specification Tested Reactivity: human, mouse, rat Cited Reactivity: human, mouse Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag10971 Product name: Recombinant human ZFP64 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 357-681 aa of BC041622 Sequence: ALRIHERIHCTDRPFKCNYCSFDTKQPSNLSKHMKKFHGDMVKTEALERKDTGRQSSRQVAKLDAKKSFHCDICDASFMREDSLRSHKRQHSEYNESKNSDVTVLQFQIDPSKQPATPLTVGHLQVPLQPSQVPQFSEGRVKIIVGHQVPQANTIVQAAAAAVNIVPPALVAQNPEELPGNSRLQILRQVSLIAPPQSSRCPSEAGAMTQPAVLLTTHEQTDGATLHQTLIPTASGGPQEGSGNQTFITSSGITCTDFEGLNALIQEGTAEVTVVSDGGQNIAVATTAPPVFSSSSQQELPKQTYSIIQGAAHPALLCPADSIPD Predict reactive species Full Name: zinc finger protein 64 homolog (mouse) Calculated Molecular Weight: 681 aa, 75 kDa Observed Molecular Weight: 70 kDa GenBank Accession Number: BC041622 Gene Symbol: ZFP64 Gene ID (NCBI): 55734 RRID: AB_2218826 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: Q9NTW7 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.