Proteintech, 17363-1-AP, ZnT3 Polyclonal antibody

Size: 20ul / 150ul The ZnT3 (17363-1-AP) by Proteintech is a Polyclonal antibody targeting ZnT3 in WB, IHC, ELISA applications with reactivity to human, mouse, rat samples 17363-1-AP targets ZnT3 in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples. Tested Applications Positive WB detected in: mouse brain tissue, rat brain tissue Positive IHC detected in: human brain tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0 Recommended dilution Western Blot (WB): WB : 1:1000-1:6000 Immunohistochemistry (IHC): IHC : 1:20-1:200 Background Information ZnT3, encoded by SLC30A3, is a member of SLC30A family which is zinc transporter sequestrating cytosolic zinc into intracellular compartments or effluxing zinc to the extracellular space. Excessive zinc level can cause neuron apoptosis and lead to cognitive impairments. Znt3 facilitates the transport and storage of zinc in synaptic vesicles. Abnormal ZnT3 expression has been linked to some neurodegenerative disorders. Specification Tested Reactivity: human, mouse, rat Cited Reactivity: human, mouse, rat Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag10735 Product name: Recombinant human SLC30A3 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 288-388 aa of BC028358 Sequence: VLRILMEGTPRNVGFEPVRDTLLSVPGVRATHELHLWALTLTYHVASAHLAIDSTADPEAVLAEASSRLYSRFGFSSCTLQVEQYQPEMAQCLRCQEPPQA Predict reactive species Full Name: solute carrier family 30 (zinc transporter), member 3 Calculated Molecular Weight: 388 aa, 42 kDa Observed Molecular Weight: 42 kDa, 48 kDa GenBank Accession Number: BC028358 Gene Symbol: ZnT3 Gene ID (NCBI): 7781 RRID: AB_2239335 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: Q99726 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.