Proteintech, 17767-1-AP, USP38 Polyclonal antibody

Size: 20ul / 150ul The USP38 (17767-1-AP) by Proteintech is a Polyclonal antibody targeting USP38 in WB, IP, ELISA applications with reactivity to human samples 17767-1-AP targets USP38 in WB, IHC, IF, IP, CoIP, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: HEK-293T cells Positive IP detected in: K-562 cells Recommended dilution Western Blot (WB): WB : 1:200-1:1000 Immunoprecipitation (IP): IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate Background Information Ubiquitin specific peptidase 38 (USP38) is a negative regulator of type I IFN signaling. USP38 can strongly induced the degradation of the active form of TBK1 after viral infection. USP38 may play a critical role in the maintenance of the balance between innate immune responses and tolerance through dynamic ubiquitin editing of TBK1 in response to viral infection and perhaps other infectious diseases or cancer. (PMID:27692986) Specification Tested Reactivity: human Cited Reactivity: human, mouse, rat Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag12172 Product name: Recombinant human USP38 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 693-1042 aa of BC068975 Sequence: VPNESNKILVNKDVPQKPGGETTPSVTDLLNYFLAPEILTGDNQYYCENCASLQNAEKTMQITEEPEYLILTLLRFSYDQKYHVRRKILDNVSLPLVLELPVKRITSFSSLSESWSVDVDFTDLSENLAKKLKPSGTDEASCTKLVPYLLSSVVVHSGISSESGHYYSYARNITSTDSSYQMYHQSEALALASSQSHLLGRDSPSAVFEQDLENKEMSKEWFLFNDSRVTFTSFQSVQKITSRFPKDTAYVLLYKKQHSTNGLSGNNPTSGLWINGDPPLQKELMDAITKDNKLYLQEQELNARARALQAASASCSFRPNGFDDNDPPGSCGPTGGGGGGGFNTVGRLVF Predict reactive species Full Name: ubiquitin specific peptidase 38 Calculated Molecular Weight: 1042 aa, 117 kDa Observed Molecular Weight: 117 kDa GenBank Accession Number: BC068975 Gene Symbol: USP38 Gene ID (NCBI): 84640 RRID: AB_2213383 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: Q8NB14 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.