Product Description
Size: 20ul / 150ul
The Piccolo (18156-1-AP) by Proteintech is a Polyclonal antibody targeting Piccolo in IF-P, ELISA applications with reactivity to human, mouse samples
18156-1-AP targets Piccolo in IF-P, ELISA applications and shows reactivity with human, mouse samples.
Tested Applications
Positive IF-P detected in: mouse brain tissue
Recommended dilution
Immunofluorescence (IF)-P: IF-P : 1:50-1:500
Background Information
Piccolo is a presynaptic scaffolding protein of the cytomatrix assembled at the active zone (AZ). AZ is a special region of the presynaptic plasma membrane where synaptic vesicles (SVs) fuse. It has been shown that Piccolo affects presynaptic function by negatively regulating SV exocytosis (PMID: 18519737).
Specification
Tested Reactivity: human, mouse
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Immunogen: CatNo: Ag12952 Product name: Recombinant human PCLO protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 1-356 aa of BC001304 Sequence: MKKFRVSLVSKVGKQKYVDLNMLSDSENSQHLELHEPPKAVDKAKSPGVDPKQLAAELQKVSLQQSPLVLSSVVEKGSHVHSGPTSAGSSSVPSPGQPGSPSVSKKKHGSSKPTDGTKVVSHPITGEIQLQINYDLGNLIIHILQARNLVPRDNNGYSDPFVKVYLLPGRGAEYKRRTKHVQKSLNPEWNQTVIYKSISMEQLKKKTLEVTVWDYDRFSSNDFLGEVLIDLSSTAHLDNTPRWYPLKEQTESIDHGKSHSSQSSQQSPKPSVIKSRSHGIFPDPSKDMQVPTIEKSHSSPGSSKSSSEGHLRSHGPSRSQSKTSVTQTHLEDAGAAIAAAEAAVQQLRIQPSKRRK Predict reactive species
Full Name: piccolo (presynaptic cytomatrix protein)
Calculated Molecular Weight: 553 kDa
GenBank Accession Number: BC001304
Gene Symbol: Piccolo
Gene ID (NCBI): 27445
RRID: AB_3085556
Conjugate: Unconjugated
Form: Liquid
Purification Method: Antigen affinity purification
UNIPROT ID: Q9Y6V0
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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