Product Description
Size: 20ul / 150ul
The PCDHAC2 (18211-1-AP) by Proteintech is a Polyclonal antibody targeting PCDHAC2 in WB, ELISA applications with reactivity to human, mouse, rat samples
18211-1-AP targets PCDHAC2 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Applications
Positive WB detected in: mouse brain tissue, rat brain tissue
Recommended dilution
Western Blot (WB): WB : 1:500-1:2000
Background Information
Protocadherins, which constitute the largest subgroup within the cadherin superfamily, are predominantly expressed in the nervous system and are probably involved in the regulation of neuronal recognition and connectivity (PMID: 17936607; 12231349; 17133224). The protocadherin subfamily can be further subdivided into three groups: the clustered protocadherins, comprising α-, β-, and γ-protocadherins; δ-protocadherins; and others, many of which are solitary (PMID: 17133224). PCDHAC2 is a subtype of α-protocadherins, mainly expressed by serotonergic neurons. PCDHAC2 is essential for the diffuse projection of serotonergic axons (PMID: 29162883).
Specification
Tested Reactivity: human, mouse, rat
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Immunogen: CatNo: Ag12889 Product name: Recombinant human PCDHAC2 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 42-406 aa of BC104776 Sequence: SQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAPSPRYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNSPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSKVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDYEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVAVLSVNDQDSGPNRKVSLGLEA Predict reactive species
Full Name: protocadherin alpha subfamily C, 2
Calculated Molecular Weight: 884 aa, 96 kDa
Observed Molecular Weight: 120 kDa
GenBank Accession Number: BC104776
Gene Symbol: PCDHAC2
Gene ID (NCBI): 56134
Conjugate: Unconjugated
Form: Liquid
Purification Method: Antigen affinity purification
UNIPROT ID: Q9Y5I4
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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