Proteintech, 18251-1-AP, PD-L2/CD273 Polyclonal antibody

Size: 20ul / 150ul The PD-L2/CD273 (18251-1-AP) by Proteintech is a Polyclonal antibody targeting PD-L2/CD273 in WB, ELISA applications with reactivity to human, mouse, rat samples 18251-1-AP targets PD-L2/CD273 in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat samples. Tested Applications Positive WB detected in: NIH/3T3 cells, mouse heart tissue, HepG2 cells, RAW 264.7 cells Recommended dilution Western Blot (WB): WB : 1:500-1:2000 Background Information Programmed cell death ligand 2 (PD-L2, also known as CD273, or B7-DC), is one of the B7 family molecules which are type I transmembrane proteins belonging to the immunoglobulin superfamily. PD-L2 was identified both by its homology to PD-L1 and by analysis of genes differentially expressed in libraries generated from dendritic cells (DC) and activated macrophages (PMID: 14515254). PD-L2 is a second ligand for PD-1, a costimulatory molecule that plays an inhibitory role in regulating T cell activation in the periphery. Specification Tested Reactivity: human, mouse, rat Cited Reactivity: human, mouse Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag13039 Product name: Recombinant human PDCD1LG2 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-273 aa of BC074766 Sequence: MIFLLLMLSLELQLHQIAALFTVTVPKELYIIEHGSNVTLECNFDTGSHVNLGAITASLQKVENDTSPHRERATLLEEQLPLGKASFHIPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVKASYRKINTHILKVPETDEVELTCQATGYPLAEVSWPNVSVPANTSHSRTPEGLYQVTSVLRLKPPPGRNFSCVFWNTHVRELTLASIDLQSQMEPRTHPTWLLHIFIPSCIIAFIFIATVIALRKQLCQKLYSSKDTTKRPVTTTKREVNSAI Predict reactive species Full Name: programmed cell death 1 ligand 2 Calculated Molecular Weight: 273 aa, 31 kDa Observed Molecular Weight: 40-50 kDa, 28 kDa GenBank Accession Number: BC074766 Gene Symbol: PD-L2 Gene ID (NCBI): 80380 RRID: AB_2878523 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: Q9BQ51 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.