Proteintech, 19524-1-AP, TICAM2 Polyclonal antibody

Size: 20ul / 150ul The TICAM2 (19524-1-AP) by Proteintech is a Polyclonal antibody targeting TICAM2 in WB, IHC, ELISA applications with reactivity to human, mouse samples 19524-1-AP targets TICAM2 in WB, IHC, ELISA applications and shows reactivity with human, mouse samples. Tested Applications Positive WB detected in: mouse brain tissue, HeLa cells, human testis tissue, PC-3 cells Positive IHC detected in: mouse testis tissue, human prostate hyperplasia tissue, mouse brain tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0 Recommended dilution Western Blot (WB): WB : 1:500-1:1000 Immunohistochemistry (IHC): IHC : 1:50-1:500 Background Information TICAM2, also named TIRAP3, TIRP, and TRAM, is involved in IL1-triggered NF-kappa-B activation, functioning upstream of IRAK1, IRAK2, TRAF6, and IKBKB. Physically bridges TLR4 and TICAM1 and functionally transmits LPS-TRL4 signal to TICAM1. TICAM2 is involved in LPS-TLR4 signaling to regulate the MYD88-independent pathway during the innate immune response to LPS.In WB, the MW of TICAM2 is about 27-32 kDa. Specification Tested Reactivity: human, mouse Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: Peptide Predict reactive species Full Name: toll-like receptor adaptor molecule 2 Calculated Molecular Weight: 27 kDa Observed Molecular Weight: 32 kDa GenBank Accession Number: NM_021649 Gene Symbol: TICAM2 Gene ID (NCBI): 353376 RRID: AB_10791887 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: Q86XR7 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.