Proteintech, 19731-1-AP, Urocortin Polyclonal antibody

Size: 20ul / 150ul The Urocortin (19731-1-AP) by Proteintech is a Polyclonal antibody targeting Urocortin in WB, IP, ELISA applications with reactivity to human samples 19731-1-AP targets Urocortin in WB, IHC, IP, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: mouse kidney tissue, HEK-293 cells, human kidney tissue, human testis tissue Positive IP detected in: mouse kidney tissue Recommended dilution Western Blot (WB): WB : 1:500-1:3000 Immunoprecipitation (IP): IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate Background Information Urocortin is a member of the sauvagine/corticotropin-releasing factor/urotensin I family that includes CRF, urotensin I, sauvagine, urocortin II and urocortin III. Urocortin is a potent anorexigenic peptide that induces fed-like motor activity when administered centrally or peripherally in fasted animals. Urocortin is also a potent and long-lasting hypotensive agent and increases coronary blood flow. Urocortin acts in vitro to stimulate the secretion of adrenocorticotropic hormone (ACTH) and binds with high affinity to CRF receptor types 1, 2-alpha, and 2-beta. Urocortin is synthesized as precursor, which is subsequently processed to the mature biologically active peptide (a 40-amino acid Molecule ). The 22 kDa may be a urocortin 1 precursor protein (PMID: 28887029). Specification Tested Reactivity: human Cited Reactivity: human Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: Peptide Predict reactive species Full Name: urocortin Calculated Molecular Weight: 13 kDa Observed Molecular Weight: 22 kDa GenBank Accession Number: NM_003353 Gene Symbol: UCN Gene ID (NCBI): 7349 RRID: AB_10640909 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: P55089 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.