Proteintech, 19957-1-AP, Huntingtin Polyclonal antibody

Size: 20ul / 150ul The Huntingtin (19957-1-AP) by Proteintech is a Polyclonal antibody targeting Huntingtin in IHC, IF/ICC, IF-P, ELISA applications with reactivity to human, mouse, rat samples 19957-1-AP targets Huntingtin in IHC, IF/ICC, IF-P, ELISA applications and shows reactivity with human, mouse, rat samples. Tested Applications Positive IHC detected in: rat cerebellum tissue, mouse brain tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0 Positive IF-P detected in: rat cerebellum tissue Positive IF/ICC detected in: HEK-293 cells, SH-SY5Y cells Recommended dilution Immunohistochemistry (IHC): IHC : 1:200-1:800 Immunofluorescence (IF)-P: IF-P : 1:50-1:500 Immunofluorescence (IF)/ICC: IF/ICC : 1:50-1:500 Background Information HTT, also named as HD and IT15, belongs to the huntingtin family. HTT may play a role in microtubule-mediated transport or vesicle function. Defects in HTT are the cause of Huntington disease (HD) which is an autosomal dominant neurodegenerative disorder characterized by involuntary movements (chorea), general motor impairment, psychiatric disorders and dementia. The antibody recognizes the C-term of HTT. Specification Tested Reactivity: human, mouse, rat Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: Peptide Predict reactive species Full Name: huntingtin Calculated Molecular Weight: 348 kDa GenBank Accession Number: NM_002111 Gene Symbol: Huntingtin Gene ID (NCBI): 3064 RRID: AB_2878629 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: P42858 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.