Proteintech, 20245-1-AP, DOCK2-Specific Polyclonal antibody

Size: 20ul / 150ul The DOCK2-Specific (20245-1-AP) by Proteintech is a Polyclonal antibody targeting DOCK2-Specific in WB, IF/ICC, ELISA applications with reactivity to human samples 20245-1-AP targets DOCK2-Specific in WB, IF/ICC, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: Jurkat cells, Ramos cells Positive IF/ICC detected in: Jurkat cells Recommended dilution Western Blot (WB): WB : 1:500-1:2000 Immunofluorescence (IF)/ICC: IF/ICC : 1:50-1:500 Background Information DOCK2, also named as KIAA0209, belongs to the DOCK family. It is involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. DOCK2 activates RAC1 and RAC2 small GTPases, probably by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. DOCK2 may also participate in IL2 transcriptional activation via the activation of RAC2. The antibody is specific to DOCK2. Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: Peptide Predict reactive species Full Name: dedicator of cytokinesis 2 Calculated Molecular Weight: 212 kDa Observed Molecular Weight: 212 kDa GenBank Accession Number: NM_004946 Gene Symbol: DOCK2 Gene ID (NCBI): 1794 RRID: AB_10699879 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: Q92608 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.