Proteintech, 20529-1-AP, FOXP2 Polyclonal antibody

Size: 20ul / 150ul The FOXP2 (20529-1-AP) by Proteintech is a Polyclonal antibody targeting FOXP2 in WB, IP, ELISA applications with reactivity to human, mouse, rat samples 20529-1-AP targets FOXP2 in WB, IHC, IF, IP, CoIP, ELISA applications and shows reactivity with human, mouse, rat samples. Tested Applications Positive WB detected in: HCT 116 cells, Neuro-2a cells, mouse brain tissue, mouse lung tissue, rat brain tissue Positive IP detected in: mouse spleen tissue Recommended dilution Western Blot (WB): WB : 1:500-1:1000 Immunoprecipitation (IP): IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate Background Information FOXP2, Forkhead box protein P2, is associated with speech and language development (PMID: 24765219). FOXP2 is expressed in the brain, lungs, heart and gut. In the brain, it is widely expressed in sensory, limbic and motor structures(PMID: 10880297, PMID:15685218). Mutations in FOXP2 caused the severe speech and language disorder developmental verbal dyspraxia (PMID: 15877281). FOXP2 was detected 2 isoforms of 70 kDa and 80-82 kDa (PMID: 15056696, PMID: 29360038, PMID: 17999357). Specification Tested Reactivity: human, mouse, rat Cited Reactivity: human, rat Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag14391 Product name: Recombinant human FOXP2 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-56 aa of BC018016 Sequence: MMQESATETISNSSMNQNGMSTLSSQLDAGSRDGRSSGDTSSEVSTVELLHLQQQQ Predict reactive species Full Name: forkhead box P2 Calculated Molecular Weight: 80 kDa Observed Molecular Weight: 70-80 kDa GenBank Accession Number: BC018016 Gene Symbol: FOXP2 Gene ID (NCBI): 93986 RRID: AB_10695756 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: O15409 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.