Proteintech, 20712-1-AP, FLT4/VEGFR3 Polyclonal antibody

Size: 20ul / 150ul The FLT4/VEGFR3 (20712-1-AP) by Proteintech is a Polyclonal antibody targeting FLT4/VEGFR3 in WB, ELISA applications with reactivity to human, mouse samples 20712-1-AP targets FLT4/VEGFR3 in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse samples. Tested Applications Positive WB detected in: mouse spleen tissue, PC-3 cells, HeLa cells, mouse heart tissue Recommended dilution Western Blot (WB): WB : 1:200-1:1000 Background Information FLT4, also named VEGFR-3, belongs to the protein kinase superfamily, Tyr protein kinase family, and CSF-1/PDGF receptor subfamily. It is a receptor for VEGFC. FLT4 has a tyrosine-protein kinase activity. Defects in FLT4 cause lymphedema hereditary type 1 (LYH1A). Defects in FLT4 are found in juvenile hemangioma. VEGFR-3 is a highly glycosylated protein and migrates as bands with different molecular weights: an ~175 kDa precursor, an ~195 kDa mature form, an ~140 kDa non-glycosylated backbone, and a form that appears to be partially cleaved proteolytically in the extracellular domain to produce an ~125 kDa band(PMID: 15389531). Specification Tested Reactivity: human, mouse Cited Reactivity: human, mouse, deer Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: Peptide Predict reactive species Full Name: fms-related tyrosine kinase 4 Calculated Molecular Weight: 153 kDa Observed Molecular Weight: 125 kDa GenBank Accession Number: NM_002020 Gene Symbol: FLT4 Gene ID (NCBI): 2324 RRID: AB_10733474 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: P35916 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.