Proteintech, 20774-1-AP, CC2D1B Polyclonal antibody

Size: 20ul / 150ul The CC2D1B (20774-1-AP) by Proteintech is a Polyclonal antibody targeting CC2D1B in WB, IP, ELISA applications with reactivity to human, mouse, rat samples 20774-1-AP targets CC2D1B in WB, IP, ELISA, IF applications and shows reactivity with human, mouse, rat samples. Tested Applications Positive WB detected in: mouse brain tissue, human placenta tissue, mouse kidney tissue, SH-SY5Y cells Positive IP detected in: mouse brain tissue Recommended dilution Western Blot (WB): WB : 1:1000-1:4000 Immunoprecipitation (IP): IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate Background Information CC2D1B/Freud2 and CC2D1A/Freud1 are two homologs belonging to the evolutionary conserved Lgd protein family that is involved in endosomal trafficking. CC2D1B has been identified as the novel repressor of postsynaptic 5-HT1A expression. The predicted molecular weight of CC2D1B is 89 kDa, but the observed molecular weight is around 120 kDa, which may be caused by post-translational modification. This antibody is specific to CC2D1B, which has been confirmed by siRNA test. (19423080 , 2672064) Specification Tested Reactivity: human, mouse, rat Cited Reactivity: human, mouse, rat Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag14767 Product name: Recombinant human CC2D1B protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 468-767 aa of BC007912 Sequence: VAATLAAAEKLASAEDSAPADKDEDEGEPPAQAPVAKKPARPTVPSSQRLPEPRASSSKESPSPSVREQLALLEARKLQYQRAALQAKRSQDLEQAKAYLRVAKWLEAQIIQARSGRPVDLSKVPSPLTDEEGDFILIHHEDLRLSQKAEEVYAQLQKMLLEQQEKCLLFSKQFMHQGNVAETTRFEKLAQDRKKQLEILQLAQAQGLDPPTHHFELKTFQTVRIFSELNSTEMHLIIVRGMNLPAPPGVTPDDLDAFVRFEFHYPNSDQAQKSKTAVVKNTNSPEFDQLFKLNINRNHR Predict reactive species Full Name: coiled-coil and C2 domain containing 1B Calculated Molecular Weight: 858 aa, 94 kDa Observed Molecular Weight: 120 kDa GenBank Accession Number: BC007912 Gene Symbol: CC2D1B Gene ID (NCBI): 200014 RRID: AB_10693627 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: Q5T0F9 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.