Proteintech, 22263-1-AP, Polycystin 1 Polyclonal antibody

Size: 20ul / 150ul The Polycystin 1 (22263-1-AP) by Proteintech is a Polyclonal antibody targeting Polycystin 1 in IHC, ELISA applications with reactivity to human, mouse samples 22263-1-AP targets Polycystin 1 in IHC, ELISA applications and shows reactivity with human, mouse samples. Tested Applications Positive IHC detected in: human liver tissue, mouse kidney tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0 Recommended dilution Immunohistochemistry (IHC): IHC : 1:50-1:500 Background Information Polycystin 1 (PC1) is also named as PKD1, and Autosomal dominant polycystic kidney disease 1 protein, and belongs to the polycystin family. PKD1 and PKD2 are formed component of a heteromeric calcium-permeable ion channel. PKD1 is considered an orphan, atypical G protein coupled receptor complexed with TRPP2 (Polycystin 2 or PKD2), a Ca2+-permeable ion channel (PMID:27214281). PKD1 is involved in renal tubulogenesis (PMID:12482949). Specification Tested Reactivity: human, mouse Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: Peptide Predict reactive species Full Name: polycystic kidney disease 1 (autosomal dominant) Calculated Molecular Weight: 463 kDa GenBank Accession Number: NM_000296 Gene Symbol: Polycystin 1/PKD1 Gene ID (NCBI): 5310 RRID: AB_2879053 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: P98161 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.