Proteintech, 22300-1-AP, MYH7B Polyclonal antibody

Size: 20ul / 150ul The MYH7B (22300-1-AP) by Proteintech is a Polyclonal antibody targeting MYH7B in WB, ELISA applications with reactivity to mouse, rat samples 22300-1-AP targets MYH7B in WB, ELISA applications and shows reactivity with mouse, rat samples. Tested Applications Positive WB detected in: mouse heart tissue, rat heart tissue Recommended dilution Western Blot (WB): WB : 1:500-1:1000 Background Information Myosin heavy chain 7b (MYH7b) is an ancient member of the myosin heavy chain motor protein family that is expressed in striated muscles. In mammalian cardiac muscle, MYH7b RNA is expressed along with two other myosin heavy chains, β-myosin heavy chain (β-MyHC) and α-myosin heavy chain (α-MyHC). However, unlike β-MyHC and α-MyHC, which are maintained in a careful balance at the protein level, the MYH7b locus does not produce a full-length protein in the heart due to a posttranscriptional exon-skipping mechanism that occurs in a tissue-specific manner (PMID: 33895132). MYH7b can be detected as about 200-230 kDa. Specification Tested Reactivity: mouse, rat Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: Peptide Predict reactive species Full Name: myosin, heavy chain 7B, cardiac muscle, beta Calculated Molecular Weight: 221 kDa Observed Molecular Weight: 200-230 kDa GenBank Accession Number: NM_020884 Gene Symbol: MYH7B Gene ID (NCBI): 57644 RRID: AB_3669394 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: A7E2Y1 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.