Proteintech, 22583-1-AP, MPDZ/MUPP1 Polyclonal antibody

Size: 20ul / 150ul The MPDZ/MUPP1 (22583-1-AP) by Proteintech is a Polyclonal antibody targeting MPDZ/MUPP1 in WB, ELISA applications with reactivity to human samples 22583-1-AP targets MPDZ/MUPP1 in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: SH-SY5Y cells, SK-N-SH cells, U-87 MG cells Recommended dilution Western Blot (WB): WB : 1:500-1:2000 Background Information The PDZ domain is a protein motif that mediates protein-protein interactions. MUPP1(multi-PDZ domain protein-1) has 13 PDZ domains, each containing the structural characteristics of a prototypic PDZ motif, but lacks a catalytic domain. MUPP1 belongs to the PDZ domain protein family and is a structural homologant of PATJ (PALS1-associated tight-linking protein) (PMID: 23880463). MUPP1 is a scaffold protein and plays an important role in cytoskeletal organization, cell polarity, and cell proliferation(PMID: 25662616). Mutations in MUPP1 are associated with congenital hydrocephalus(PMID: 23240096). Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag18222 Product name: Recombinant human MUPP1 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 751-1100 aa of BC140793 Sequence: LMFVNDVNLENSSLEEAVEALKGAPSGTVRIGVAKPLPLSPEEGYVSAKEDSFLYPPHSCEEAGLADKPLFRADLALVGTNDADLVDESTFESPYSPENDSIYSTQASILSLHGSSCGDGLNYGSSLPSSPPKDVIENSCDPVLDLHMSLEELYTQNLLQRQDENTPSVDISMGPASGFTINDYTPANAIEQQYECENTIVWTESHLPSEVISSAELPSVLPDSAGKGSEYLLEQSSLACNAECVMLQNVSKESFERTINIAKGNSSLGMTVSANKDGLGMIVRSIIHGGAISRDGRIAIGDCILSINEESTISVTNAQARAMLRRHSLIGPDIKITYVPAEHLEEFKIS Predict reactive species Full Name: multiple PDZ domain protein Calculated Molecular Weight: 2070 aa, 222 kDa Observed Molecular Weight: 250 kDa GenBank Accession Number: BC140793 Gene Symbol: MPDZ Gene ID (NCBI): 8777 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: O75970 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.