Proteintech, 23838-1-AP, ANXA2R Polyclonal antibody

Size: 20ul / 150ul The ANXA2R (23838-1-AP) by Proteintech is a Polyclonal antibody targeting ANXA2R in IHC, ELISA applications with reactivity to human samples 23838-1-AP targets ANXA2R in WB, IHC, ELISA applications and shows reactivity with human samples. Tested Applications Positive IHC detected in: human prostate cancer tissue, human brain tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0 Recommended dilution Immunohistochemistry (IHC): IHC : 1:20-1:200 Background Information ANXA2R (annexin A2 receptor) is a receptor protein that interacts with annexin A2 (ANXA2). ANXA2R plays significant roles in various diseases. For instance, in renal cell carcinoma (RCC), high expression of ANXA2R is associated with poor prognosis. A recent study published in Nature revealed that SP140 regulates interferon mRNA stability and antiviral immunity by inhibiting a novel regulator, RESIST, which decreases the stability of Ifnb1 mRNA and thereby suppresses interferon expression. Notably, RESIST is the orthologue of human ANXA2R. This finding highlights the crucial role of ANXA2R in cellular signaling and immune responses. Specification Tested Reactivity: human Cited Reactivity: human Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag20807 Product name: Recombinant human C5orf39 protein Source: e coli. -derived, PET30a Tag: 6*His Domain: 1-193 aa of BC067873 Sequence: MEQHFLGCVKRAWDSAEVAPEPQPPPIVSSEDRGPWPLPLYPVLGEYSLDSCDLGLLSSPCWRLPGVYWQNGLSPGVQSTLEPSTAKPTEFSWPGTQKQQEAPVEEVGQAEEPDRLRLRQLPWSSPLHPWDRQQDTEVCDSGCLLERRHPPALQPWRHLPGFSDCLEWILRVGFAAFSVLWACCSRICGAKQP Predict reactive species Full Name: chromosome 5 open reading frame 39 Calculated Molecular Weight: 193 aa, 22 kDa GenBank Accession Number: BC067873 Gene Symbol: ANXA2R Gene ID (NCBI): 389289 RRID: AB_2879333 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen Affinity purified UNIPROT ID: Q3ZCQ2 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.