Product Description
Size: 20ul / 150ul
The BRIP1(N-terminal) (24436-1-AP) by Proteintech is a Polyclonal antibody targeting BRIP1(N-terminal) in WB, ELISA applications with reactivity to human, mouse samples
24436-1-AP targets BRIP1(N-terminal) in WB, ELISA applications and shows reactivity with human, mouse samples.
Tested Applications
Positive WB detected in: HeLa cells, MCF-7 cells
Recommended dilution
Western Blot (WB): WB : 1:500-1:2000
Background Information
BRIP1 also named as BACH1, FANCJ or ATP dependent RNA helicase BRIP1 is a 1249 amino acid protein, which contains one helicase ATP-binding domain and belongs to the DEAD box heilicase family, DEAH subfamily. BRIP1 contains nuclear localization signal and is ubiquitously expressed with highest levels in testis, an expression pattern similar to that of BRCA1. BRIP1 is required to resolve the secondary structures of guanine-rich DNA that occasionally form during lagging-strand DNA synthesis.
Specification
Tested Reactivity: human, mouse
Cited Reactivity: human
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Immunogen: CatNo: Ag19907 Product name: Recombinant human BRIP1 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 1-342 aa of BC101472 Sequence: MSSMWSEYTIGGVKIYFPYKAYPSQLAMMNSILRGLNSKQHCLLESPTGSGKSLALLCSALAWQQSLSGKPADEGVSEKAEVQLSCCCACHSKDFTNNDMNQGTSRHFNYPSTPPSERNGTSSTCQDSPEKTTLAAKLSAKKQASIYRDENDDFQVEKKRIRPLETTQQIRKRHCFGTEVHNLDAKVDSGKTVKLNSPLEKINSFSPQKPPGHCSRCCCSTKQGNSQESSNTIKKDHTGKSKIPKIYFGTRTHKQIAQITRELRRTAYSGVPMTILSSRDHTCVHPEVVGNFNRNEKCMELLDGKNGKSCYFYHGVHKISDQHTLQTFQGMCKAWDIEELVS Predict reactive species
Full Name: BRCA1 interacting protein C-terminal helicase 1
Calculated Molecular Weight: 1249 aa, 141 kDa
Observed Molecular Weight: 140-150 kDa
GenBank Accession Number: BC101472
Gene Symbol: BACH1/BRIP1
Gene ID (NCBI): 83990
RRID: AB_2879548
Conjugate: Unconjugated
Form: Liquid
Purification Method: Antigen affinity purification
UNIPROT ID: Q9BX63
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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