Product Description
Size: 20ul / 150ul
The SEC61 Alpha (24935-1-AP) by Proteintech is a Polyclonal antibody targeting SEC61 Alpha in WB, ELISA applications with reactivity to human, mouse samples
24935-1-AP targets SEC61 Alpha in WB, IF, CoIP, ELISA applications and shows reactivity with human, mouse samples.
Tested Applications
Positive WB detected in: mouse brain tissue, HEK-293 cells, U2OS cells, mouse liver tissue
Recommended dilution
Western Blot (WB): WB : 1:500-1:1000
Background Information
The SEC61 complex is a major component of the endoplasmic reticulum (ER) translocation site (PMID: 7720858). This complex is composed of three subunits: SEC61alpha, SEC61beta and SEC61gamma. SEC61alpha is a polytopic integral membrane protein. It is a core component of the ER translocation complex, playing a crucial role in the insertion of secretory and membrane polypeptides into the ER (PMID: 9512475).
Specification
Tested Reactivity: human, mouse
Cited Reactivity: human, rat
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Immunogen: CatNo: Ag20779 Product name: Recombinant human SEC61A2 protein Source: e coli. -derived, PET30a Tag: 6*His Domain: 190-418 aa of BC026179 Sequence: TIVWKAFSPTTINTGRGTEFEGAVIALFHLLATRTDKVRALREAFYRQNLPNLMNLIATVFVFAVVIYFQGFRVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLSVRFSGNFLVNLLGQWADVSGGGPARSYPVGGLCYYLSPPESMGAIFEDPVHVVVYIIFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRDTSMVHELNSARA Predict reactive species
Full Name: Sec61 alpha 2 subunit (S. cerevisiae)
Calculated Molecular Weight: 52 kDa
Observed Molecular Weight: 52 kDa
GenBank Accession Number: BC026179
Gene Symbol: SEC61 Alpha
Gene ID (NCBI): 55176
RRID: AB_2879807
Conjugate: Unconjugated
Form: Liquid
Purification Method: Antigen affinity purification
UNIPROT ID: Q9H9S3
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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