Product Description
Size: 20ul / 150ul
The PFN3 (25188-1-AP) by Proteintech is a Polyclonal antibody targeting PFN3 in WB, ELISA applications with reactivity to human, mouse, rat samples
25188-1-AP targets PFN3 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Applications
Positive WB detected in: mouse testis tissue, rat testis tissue
Recommended dilution
Western Blot (WB): WB : 1:500-1:2000
Background Information
PFN3 also known as profilin-3, belongs to the profilin family, a family of actin-binding proteins that regulate the dynamics of actin in cells. PFN3 may be involved in spermatogenesis. (PMID: 11867228). Deletion or abnormal function of PFN3 may lead to male infertility, especially in disorders associated with abnormal sperm acrosome development (spherozoospermia)(PMID: 34869336).
Specification
Tested Reactivity: human, mouse, rat
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Immunogen: CatNo: Ag18131 Product name: Recombinant human PFN3 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-137 aa of BC132952 Sequence: MGDWKVYISAVLRDQRIDDVAIVGHADNSCVWASRPGGLLAAISPQEVGVLTGPDRHTFLQAGLSVGGRRCCVIRDHLLAEGDGVLDARTKGLDARAVCVGRAPRALLVLMGRRGVHGGILNKTVHELIRGLRMQGA Predict reactive species
Full Name: profilin 3
Calculated Molecular Weight: 137 aa, 15 kDa
Observed Molecular Weight: 14 kDa
GenBank Accession Number: BC132952
Gene Symbol: PFN3
Gene ID (NCBI): 345456
Conjugate: Unconjugated
Form: Liquid
Purification Method: Antigen affinity purification
UNIPROT ID: P60673
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
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