Proteintech, 25220-1-AP, SLMAP Polyclonal antibody

Size: 20ul / 150ul The SLMAP (25220-1-AP) by Proteintech is a Polyclonal antibody targeting SLMAP in WB, ELISA applications with reactivity to human, mouse samples 25220-1-AP targets SLMAP in WB, ELISA applications and shows reactivity with human, mouse samples. Tested Applications Positive WB detected in: mouse heart tissue, A431 cells, mouse skeletal muscle tissue Recommended dilution Western Blot (WB): WB : 1:500-1:1000 Background Information Sarcolemmal membrane associated protein (SLMAP) is a tail-anchored membrane protein involved in the docking and membrane fusion process via protein-protein interactions. Deregulation of SLMAP expression plays an important role in type 2 diabetes, and changes in SLMAP expression are linked to hyperglycemia and diabetes. SLMAPs are components of cardiac membranes and have been identified as a novel regulator of cardiac function. There are several isoforms of SLMAPs with varying molecular size (35, 45, 63, and 83-91 kDa) as a result of alternative splicing. The short 35-kDa isoform is predominantly expressed in cardiac and slow-twitch skeletal muscle, while the 83- to 91-kDa isoform is ubiquitous. This antibody recognizes all of these isoforms in mouse heart lysate. (21785580, 22180652) Specification Tested Reactivity: human, mouse Cited Reactivity: human Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag18162 Product name: Recombinant human SLMAP protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 479-828 aa of BC115701 Sequence: VSLLKDDLQGAQSEIEAKQEIQHLRKELIEAQELARTSKQKCFELQALLEEERKAYRNQVEESTKQIQVLQAQLQRLHIDTENLREEKDSEITSTRDELLSARDEILLLHQAAAKVASERDTDIASLQEELKKVRAELERWRKAASEYEKEITSLQNSFQLRCQQCEDQQREEATRLQGELEKLRKEWNALETECHSLKRENVLLSSELQRQEKELHNSQKQSLELTSDLSILQMSRKELENQVGSLKEQHLRDSADLKTLLSKAENQAKDVQKEYEKTQTVLSELKLKFEMTEQEKQSITDELKQCKNNLKLLREKGNNKPWPWMPMLAALVAVTAIVLYVPGLARASP Predict reactive species Full Name: sarcolemma associated protein Calculated Molecular Weight: 828 aa, 95 kDa Observed Molecular Weight: 35 kDa, 45 kDa, 63-66 kDa, 83-91 kDa GenBank Accession Number: BC115701 Gene Symbol: SLMAP Gene ID (NCBI): 7871 RRID: AB_2879968 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: Q14BN4 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.