Product Description
Size: 20ul / 150ul
The KCND3 (25468-1-AP) by Proteintech is a Polyclonal antibody targeting KCND3 in WB, IHC, ELISA applications with reactivity to human, mouse, rat samples
25468-1-AP targets KCND3 in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Applications
Positive WB detected in: rat brain tissue, 37℃ incubated rat brain tissue
Positive IHC detected in: mouse brain tissue, mouse cerebellum tissue, rat brain tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0
Recommended dilution
Western Blot (WB): WB : 1:500-1:1000
Immunohistochemistry (IHC): IHC : 1:50-1:500
Background Information
KCND3 gene encodes the voltage-gated potassium ion channel subfamily D member 3, a six trans-membrane protein (Kv4.3), involved in the transient outward K+ current. KCND3 gene defect causes both cardiological and neurological syndromes. Kv4.3 contributes to the cardiac transient outward potassium current (Ito1), the main contributing current to the repolarizing phase 1 of the cardiac action potential.
Specification
Tested Reactivity: human, mouse, rat
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Immunogen: CatNo: Ag22183 Product name: Recombinant human KCND3 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 602-636 aa of BC113477 Sequence: PALTPEGESRPPPASPGPNTNIPSIASNVVKVSAL Predict reactive species
Full Name: potassium voltage-gated channel, Shal-related subfamily, member 3
Calculated Molecular Weight: 655 aa, 73 kDa
Observed Molecular Weight: 73 kDa
GenBank Accession Number: BC113477
Gene Symbol: KCND3
Gene ID (NCBI): 3752
RRID: AB_3669478
Conjugate: Unconjugated
Form: Liquid
Purification Method: Antigen affinity purification
UNIPROT ID: Q9UK17
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
Mobile/WhatsApp/Wechat: +86-17717886924