Proteintech, 25690-1-AP, DPYD Polyclonal antibody

Size: 20ul / 150ul The DPYD (25690-1-AP) by Proteintech is a Polyclonal antibody targeting DPYD in WB, ELISA applications with reactivity to mouse samples 25690-1-AP targets DPYD in WB, ELISA applications and shows reactivity with mouse samples. Tested Applications Positive WB detected in: mouse liver tissue Recommended dilution Western Blot (WB): WB : 1:1000-1:6000 Background Information The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Specification Tested Reactivity: mouse Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag20885 Product name: Recombinant human DPYD protein Source: e coli. -derived, PET30a Tag: 6*His Domain: 1-173 aa of BC008379 Sequence: MAPVLSKDSADIESILALNPRTQTHATLCSTSAKKLDKKHWKRNPDKNCFNCEKLENNFDDIKHTTLGERGALREAMRCLKCADAPCQKSCPTNLDIKSFITSIANKNYYGAAKMIFSDNPLGLTCGMVCPTSDLCVGGCNLYATEEGPINIGGLQQFATETLILAFSLMNHL Predict reactive species Full Name: dihydropyrimidine dehydrogenase Calculated Molecular Weight: 1025 aa, 111 kDa Observed Molecular Weight: 111 kDa GenBank Accession Number: BC008379 Gene Symbol: DPYD Gene ID (NCBI): 1806 RRID: AB_3085814 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: Q12882 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.