Product Description
Size: 20ul / 150ul
The Whirlin (25881-1-AP) by Proteintech is a Polyclonal antibody targeting Whirlin in WB, ELISA applications with reactivity to human samples
25881-1-AP targets Whirlin in WB, ELISA applications and shows reactivity with human samples.
Tested Applications
Positive WB detected in: COLO 320 cells
Recommended dilution
Western Blot (WB): WB : 1:500-1:2000
Background Information
Whirlin, also known as WHRN, DFNB31, and CIP98, is a cytoskeletal scaffold protein that plays an important role in the visual and auditory systems. In retina photoreceptors, Whirlin is required for the maintenance of periciliary membrane complexes that regulate intracellular protein transport. Mutations in Whirlin are associated with autosomal recessive nonsyndromic deafness and Usher syndrome(PMID: 17171570, 15841483).
Specification
Tested Reactivity: human
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Immunogen: CatNo: Ag22807 Product name: Recombinant human DFNB31 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 558-907 aa of BC014524 Sequence: NINALPDVSVDDVRSTSQGLSSFKPLPRPPPLAQGNDLPLGQPRKLGREDLQPPSSTPSCSGTVFSAPQNRSPPAGTAPTPGTSSAQDLPSSPIYASVSPANPSSKRPLDAHLALVNQHPIGPFPRVQSPPHLKSPSAEATVAGGCLLPPSPSGHPDQTGTNQHFVMVEVHRPDSEPDVNEVRALPQTRTSTLSQLSDSGQTLSEDSGVDAGEAEASAPGRGRQSASTKSRSSKELPRNERPTDGANKPPGLLEPTSTLVRVKKSAATLGIAIEGGANTRQPLPRIVTIQRGGSAHNCGQLKVGHVILEVNGLTLRGKEHREAARIIAEAFKTKDRDYIDFLVTEFNVML Predict reactive species
Full Name: deafness, autosomal recessive 31
Calculated Molecular Weight: 907 aa, 97 kDa
Observed Molecular Weight: 46-50 kDa
GenBank Accession Number: BC014524
Gene Symbol: Whirlin
Gene ID (NCBI): 25861
RRID: AB_2880280
Conjugate: Unconjugated
Form: Liquid
Purification Method: Antigen affinity purification
UNIPROT ID: Q9P202
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
Mobile/WhatsApp/Wechat: +86-17717886924