Product Description
Size: 20ul / 150ul
The MPIG6B (26131-1-AP) by Proteintech is a Polyclonal antibody targeting MPIG6B in WB, ELISA applications with reactivity to human samples
26131-1-AP targets MPIG6B in WB, ELISA applications and shows reactivity with human samples.
Tested Applications
Positive WB detected in: human peripheral blood platelets
Recommended dilution
Western Blot (WB): WB : 1:500-1:1000
Background Information
C6orf25, also called G6B, is an inhibitory receptor expressed on the surface of platelets,and it acts as a critical regulator of hematopoietic lineage differentiation, megakaryocyte function and platelet production (PMID: 17311996; 12665801; 27743390). C6orf25 has seven isoforms. Isoform B is the only isoform to contain both a transmembrane region and 2 immunoreceptor tyrosine-based inhibitor motifs (ITIMs) and, thus, the only one which probably has a role of inhibitory receptor. Isoform A may be the activating counterpart of isoform B (PMID: 11544253).
Specification
Tested Reactivity: human
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Immunogen: CatNo: Ag23442 Product name: Recombinant human C6orf25 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-131 aa of BC113719 Sequence: MAVFLQLLPLLLSRAQGNPGASLDGRPGDRVNLSCGGVSHPIRWVWAPSFPACKGLSKGRRPILWASSSGTPTVPPLQPFVGRLRSLDSGIRRLELLLSAGDSGTFFCKGRHEDESRTVLHVLGDRTYCKA Predict reactive species
Full Name: chromosome 6 open reading frame 25
Observed Molecular Weight: 24-29 kDa
GenBank Accession Number: BC113719
Gene Symbol: C6orf25
Gene ID (NCBI): 80739
RRID: AB_3669524
Conjugate: Unconjugated
Form: Liquid
Purification Method: Antigen affinity purification
UNIPROT ID: O95866
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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