Proteintech, 26219-1-AP, DRC1 Polyclonal antibody

Size: 20ul / 150ul The DRC1 (26219-1-AP) by Proteintech is a Polyclonal antibody targeting DRC1 in WB, IF/ICC, ELISA applications with reactivity to human, mouse, rat samples 26219-1-AP targets DRC1 in WB, IF/ICC, ELISA applications and shows reactivity with human, mouse, rat samples. Tested Applications Positive WB detected in: mouse testis tissue, rat testis tissue Positive IF/ICC detected in: hTERT-RPE1 cells Recommended dilution Western Blot (WB): WB : 1:1000-1:6000 Immunofluorescence (IF)/ICC: IF/ICC : 1:50-1:500 Background Information DRC1, also known as C2orf39, CCDC164, has 3 coiled-coil motifs in its N-terminal half and an additional coiled-coil motif near its C terminus. DRC1 is a subunit of the nexin-dynein regulatory complex, an axonemal structure critical for the regulation of ciliary dynein motors. DRC1 is predominantly expressed in the lung, brain, and prostate (PMID: 23354437). DRC1 deficiency disrupts the assembly of the nexin-dynein regulatory complex, causing ciliary dyskinesia(PMID: 23354437, 34815526). Specification Tested Reactivity: human, mouse, rat Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag24113 Product name: Recombinant human C2orf39 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 391-740 aa of BC009488 Sequence: ALIDDEKFREIWLMNEEEAKDLIARAFDVDRIIHTHHLGLPWAAPDFWFLNNVGPISQQPQKSATQIVEEMLMRSEEEEAEEAAAEPESYLDLPKQISEKTTKRILMLLCDESGFLIESKLLSLLLPLEQNECYLLRLDAIFSALGIESEDDLYKLVNFFLKYRAHRLSSSLQIKPCSQASMEKASMEETSTRSELELAEQTEMEGEKEESLVEGEKEEEEETPPSPWVIHPNDVLKILEAFVMGLKKPRDSRAPLRVQKNVRDNSKDSEYWQALTTVIPSSKQNLWDALYTALEKYHLVLTQRAKLLLENSSLEQQNTELQALLQQYLNSKINSELQVPPTQVLRVPTK Predict reactive species Full Name: chromosome 2 open reading frame 39 Observed Molecular Weight: 87 kDa GenBank Accession Number: BC009488 Gene Symbol: C2orf39/DRC1 Gene ID (NCBI): 92749 RRID: AB_3085848 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: Q96MC2 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.