Product Description
Size: 20ul / 150ul
The DTWD1 (26810-1-AP) by Proteintech is a Polyclonal antibody targeting DTWD1 in WB, ELISA applications with reactivity to human samples
26810-1-AP targets DTWD1 in WB, ELISA applications and shows reactivity with human samples.
Tested Applications
Positive WB detected in: HeLa cells
Recommended dilution
Western Blot (WB): WB : 1:500-1:2000
Background Information
DTW domain-containing protein 1 (DTWD1), also named as tRNA-uridine aminocarboxypropyltransferase 1, is responsible for 3-(3-amino-3-carboxypropyl)uridine modification at position 20 in the D-loop of certain tRNAs (PMID: 31804502; 37745798). DTWD1 has been identified as a target gene of p53 and functions as a tumor suppressor gene (PMID: 25973305). Dysregulated expression of DTWD1 has been reported in several malignancies, including gastric cancer and colorectal cancer (PMID: 25973305; 31924336).
Specification
Tested Reactivity: human
Cited Reactivity: human
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Immunogen: CatNo: Ag25170 Product name: Recombinant human DTWD1 protein Source: e coli. -derived, PET30a Tag: 6*His Domain: 1-304 aa of BC032535 Sequence: MSLNPPIFLKRSEENSSKFVETKQSQTTSIASEDPLQNLCLASQEVLQKAQQSGRSKCLKCGGSRMFYCYTCYVPVENVPIEQIPLVKLPLKIDIIKHPNETDGKSTAIHAKLLAPEFVNIYTYPCIPEYEEKDHEVALIFPGPQSISIKDISFHLQKRIQNNVRGKNDDPDKPSFKRKRTEEQEFCDLNDSKCKGTTLKKIIFIDSTWNQTNKIFTDERLQGLLQVELKTRKTCFWRHQKGKPDTFLSTIEAIYYFLVDYHTDILKEKYRGQYDNLLFFYSFMYQLIKNAKCSGDKETGKLTH Predict reactive species
Full Name: DTW domain containing 1
Calculated Molecular Weight: 35 kDa
Observed Molecular Weight: 35 kDa
GenBank Accession Number: BC032535
Gene Symbol: DTWD1
Gene ID (NCBI): 56986
RRID: AB_3085907
Conjugate: Unconjugated
Form: Liquid
Purification Method: Antigen affinity purification
UNIPROT ID: Q8N5C7
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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