Product Description
Size: 20ul / 150ul
The NKAP (27437-1-AP) by Proteintech is a Polyclonal antibody targeting NKAP in WB, ELISA applications with reactivity to human samples
27437-1-AP targets NKAP in WB, ELISA applications and shows reactivity with human samples.
Tested Applications
Positive WB detected in: A549 cells, HeLa cells, Jurkat cells, K-562 cells
Recommended dilution
Western Blot (WB): WB : 1:500-1:2000
Background Information
NKAP is a multifunctional nuclear protein that is involved in the activation of the ubiquitous transcription factor NF-kappaB. NKAP is associated with the the histone deacetylase HDAC3 and with the Notch corepressor complex, and it thereby acts as a transcriptional repressor of Notch target genes. It is also required for alphabeta T cell development. A related pseudogene has been identified on chromosome X, while a related and intronless retrocopy, which has an intact CDS and may be functional, is located on chromosome 6.
Specification
Tested Reactivity: human
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Immunogen: CatNo: Ag26637 Product name: Recombinant human NKAP protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-122 aa of BC015354 Sequence: MAPVSGSRSPDREASGSGGRRRSSSKSPKPSKSARSPRGRRSRSHSCSRSGDRNGLTHQLGGLSQGSRNQSYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLLDKER Predict reactive species
Full Name: NFKB activating protein
Calculated Molecular Weight: 415 aa, 47 kDa
Observed Molecular Weight: 47-50 kDa
GenBank Accession Number: BC015354
Gene Symbol: NKAP
Gene ID (NCBI): 79576
RRID: AB_3085959
Conjugate: Unconjugated
Form: Liquid
Purification Method: Antigen affinity purification
UNIPROT ID: Q8N5F7
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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