Proteintech, 28000-1-AP, KCNQ5 Polyclonal antibody

Size: 20ul / 150ul The KCNQ5 (28000-1-AP) by Proteintech is a Polyclonal antibody targeting KCNQ5 in WB, IP, ELISA applications with reactivity to human, mouse, rat samples 28000-1-AP targets KCNQ5 in WB, IP, ELISA applications and shows reactivity with human, mouse, rat samples. Tested Applications Positive WB detected in: Calu-1 cells, HEL cells, Raji cells, mouse brain tissue, rat brain tissue Positive IP detected in: Raji cells Recommended dilution Western Blot (WB): WB : 1:1000-1:4000 Immunoprecipitation (IP): IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate Background Information Potassium voltage-gated channel subfamily Q member 5 (KCNQ5, also known as Kv7.5 and MRD46) is widely expressed in the brain and generates M-type current. It has a role in the regulation of neuronal excitability (PMID: 10816588). KCNQ5 mutations are associated with increased excitability and decreased repolarization reserve, lead to pathophysiology (PMID: 28669405). Specification Tested Reactivity: human, mouse, rat Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag27622 Product name: Recombinant human KCNQ5 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 785-932 aa of NM_001160130 Sequence: MVASKENVQVAQSNLTKDRSMRKSFDMGGETLLSVCPMVPKDLGKSLSVQNLIRSTEELNIQLSGSESSGSRGSQDFYPKWRESKLFITDEEVGPEETETDTFDAAPQPAREAAFASDSLRTGRSRSSQSICKAGESTDALSLPHVKLK Predict reactive species Full Name: potassium voltage-gated channel, KQT-like subfamily, member 5 Calculated Molecular Weight: 102 kDa Observed Molecular Weight: 100 kDa GenBank Accession Number: NM_001160130 Gene Symbol: KCNQ5 Gene ID (NCBI): 56479 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: Q9NR82 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.