Proteintech, 28307-1-AP, RBM48 Polyclonal antibody

Size: 20ul / 150ul The RBM48 (28307-1-AP) by Proteintech is a Polyclonal antibody targeting RBM48 in WB, IF/ICC, ELISA applications with reactivity to human, mouse samples 28307-1-AP targets RBM48 in WB, IF/ICC, ELISA applications and shows reactivity with human, mouse samples. Tested Applications Positive WB detected in: mouse brain tissue, mouse testis tissue Positive IF/ICC detected in: A431 cells Recommended dilution Western Blot (WB): WB : 1:500-1:2000 Immunofluorescence (IF)/ICC: IF/ICC : 1:50-1:500 Background Information RBM48 (RNA Binding Motif Protein 48) is a gene encoding an RNA-binding protein, belonging to the RNA-binding motif protein family, which plays an important role in the splicing process of U12-type introns. Deletion of RBM48 leads to an increase in the retention of U12-type introns, which affects cell differentiation and proliferation. And mutations in RBM48 are associated with a variety of diseases. For example, U12 intron splicing defects are associated with myelodysplastic syndromes (MDS) and may increase the risk of acute myeloid leukemia (AML). RBM48 may serve as a prognostic marker in certain cancers, such as renal smoky cell carcinoma, renal clear cell carcinoma, and hepatocellular carcinoma. Specification Tested Reactivity: human, mouse Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag27277 Product name: Recombinant human C7orf64 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 68-367 aa of BC104865 Sequence: LYGAIEQYNALDEYPAEDFTEVYLIKFMNLQSARTAKRKMDEQSFFGGLLHVCYAPEFETVEETRKKLQMRKAYVVKTTENKDHYVTKKKLVTEHKDTEDFRQDFHSEMSGFCKAALNTSAGNSNPYLPYSCELPLCYFSSKCMCSSGGPVDRAPDSSKDGRNHHKTMGHYNHNDSLRKTQINSLKNSVACPGAQKAITSSEAVDRFMPRTTQLQERKRRREDDRKLGTFLQTNPTGNEIMIGPLLPDISKVDMHDDSLNTTANLIRHKLKEVISSVPKPPEDKPEDVHTSHPLKQRRRI Predict reactive species Full Name: chromosome 7 open reading frame 64 Observed Molecular Weight: 40 kDa GenBank Accession Number: BC104865 Gene Symbol: C7orf64 Gene ID (NCBI): 84060 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: Q5RL73 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.