Product Description
Size: 20ul / 150ul
The FUNDC1 (28519-1-AP) by Proteintech is a Polyclonal antibody targeting FUNDC1 in WB, ELISA applications with reactivity to human, mouse, rat samples
28519-1-AP targets FUNDC1 in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Applications
Positive WB detected in: RAW 264.7 cells, A-673 cells, mouse brain tissue, mouse liver tissue, rat brain tissue, rat liver tissue, C6 cells
Recommended dilution
Western Blot (WB): WB : 1:5000-1:20000
Background Information
FUNDC1 is a novel mitochondrial-associated membrane (MAM) protein, enriched at the MAM by interacting with the ER resident protein CANX (calnexin) under hypoxia. As mitophagy proceeds, it dissociates from CANX and preferably recruits DNM1L/DRP1 to drive mitochondrial fission in response to hypoxic stress.
Specification
Tested Reactivity: human, mouse, rat
Cited Reactivity: human, mouse, rat, monkey, goat
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Immunogen: CatNo: Ag29358 Product name: Recombinant human FUNDC1 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 96-155 aa of BC042813 Sequence: QIDWKRVEKDVNKAKRQIKKRANKAAPEINNLIEEATEFIKQNIVISSGFVGGFLLGLAS Predict reactive species
Full Name: FUN14 domain containing 1
Calculated Molecular Weight: 155 aa, 17 kDa
Observed Molecular Weight: 17 kDa
GenBank Accession Number: BC042813
Gene Symbol: FUNDC1
Gene ID (NCBI): 139341
RRID: AB_2935469
Conjugate: Unconjugated
Form: Liquid
Purification Method: Antigen affinity purification
UNIPROT ID: Q8IVP5
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
Mobile/WhatsApp/Wechat: +86-17717886924